Bromhexin 8

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Barcode: 8935206094299
Description

COMPOSITION:

Bromhexine hydrochloride ............... 8 mg

Excipients q.s ...............................1 tablet

(Lactose, wheat starch, sodium starch glycolate, magnesium stearate, PVP K30).

DOSAGE FORM: Tablet.

PRESENTATION: Box of 3 blisters x 10 tablets.

 

ACTIONS: Bromhexine hydrochloride is a mucolytic agent. It activates sialomucin synthesis and breaks down acid mucopolysaccharide fibers; so it makes the sputum thinner and less viscid. Bromhexine showed to disintegrate mucus to help expectoration and relieve cough easily.

Bromhexine is well absorbed from the gastro-intestinal tract. Food enhances Bromhexine's bioavailability. The drug is highly bound to plasma proteins (more than 95%). It is mainly metabolized via liver. Bromhexine is excreted mainly in the kidney as metabolites. The elimination of bromhexine via faeces is very low, just about 4% of the dose.

INDICATIONS: For the treatment of cases accompanied with mucus secretion disorder, particularly in acute bronchitis, acute course of chronic bronchitis.

CONTRAINDICATIONS: Hypersensitivity to Bromhexine.

PRECAUTIONS:

Avoid using in combination with antitussives because it may cause a risk of sputum stagnancy in the respiratory tract.

In patients with asthma because Bromhexin may induce bronchial spasm in some people who are easily hypersensitive.

In patients with renal, hepatic impairment.

In fatigue patients, weak habitus with no ability to expectorate.

Patients with a known history of gastrohelcoma.

PREGNANCY AND LACTATION:

Bromhexine is not recommended for these subjects due to lack of information.

VEHICLE DRIVERS AND MACHINERY OPERATORS: Cautions should be taken when driving vehicles and operating machinery because the drug may induce headache, vertigo.

INTERACTIONS: Administration of bromhexine together with antibiotics leads to higher antibiotic concentration in the lung and bronchus tissue; therefore, it is used incombination with antibiotics in the treatment of respiratory infections.

Avoid combination of Bromhexine with antitussives or drugs reducing Atropine-like bronchial mucus secretion.

ADVERSE EFFECTS: Stomachalgia, nausea, vomiting, and gastrointestinal disturbances, dryness of mouth.

Inform your physician about any adverse effects during the treatment.

OVERDOSAGE: No symptoms of overdosage have been reported in man to date. If they occur, symptomatic and supportive treatment should be provided.

 

DOSAGE & ADMINISTRATION: Adults and children over 12 years: 1 tablet x 3 times daily

- Children from 6 to 12 years of age: 1/2 tablet x 3 times daily.

- Children from 2 to 6 years of age: 1/2 tablet twice daily.

Take the drug immediately after meals.

Or as directed by the physician.

Read the directions carefully before use.

Consult the physician for more information.

Shelf-life: 36 months from the manufacturing date.

Storage conditions: Store in dry places, not exceeding 300C, protect from light.

Specifications: Manufacturer's.

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