TPCN Unikids Kẽm

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TPCN Unikids Kẽm
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Description

UNIKIDS ZINC 70

COMPOSITION:

Zinc gluconate ......... 70 mg

(Equivalent to 10 mg of zinc)

Excipients q.s ...... 1 sachet

(Sucrose, PVP K30, aerosil, orange-flavored powder, strawberry-flavored powder, tutti frutti flavor, aspartame).

DOSAGE FORM: Granules for oral suspension.

PRESENTATION: Box of 24 sachets x 1.5 g

Box of 50 sachets x 1.5 g. Box of 100 sachets x 1.5 g.

PHARMACODYNAMICS:

Zinc is an essential mineral which is present in every cell. A human body contains approximately 2 to 3 g of zinc found in bone, teeth, hair, skin, liver, muscle, white cells, and testicle. Zinc stimulates the activities of enzymes which are catalysts of biological reactions in the body. Zinc is necessary for a healthy immune system with possibility of anti-infections and flu prevention. Zinc helps to heal wounds quickly, stimulate the growth of new cells, and restore cells wounded by free radicals. Zinc is also essential for DNA synthesis, stimulates the metabolism of vitamin A and the activities of vision and central nervous system.

In addition, zinc supports the growth and development of height in children and adolescents.

Children with protracted diarrhoea lose a significant amount of zinc. The reduction of zinc in the body delays the reproduction and restoration processes of structures and functions of intestinal mucosal cells resulting in extending the diarrhea condition. Therefore, the supplement of zinc is able to reduce diarrhoea in children with protracted diarrhoea.

PHARMACOKINETICS:

Absorption of zinc from the gastrointestinal tract is incomplete; bioavailability of dietary zinc is about 20 to 30%. Zinc is distributed throughout the body with the highest concentrations found in muscle, bone, skin, eye, and prostatic fluids. It is primarily excreted in the faeces; small amounts are lost in urine and perspiration.

INDICATIONS:

Adding zinc to daily dietary, enhancing the resistance for a healthy body.

Children with acute and chronic diarrhea (combining with oral rehydration salts solution in regimen of protracted diarrhoea treatment recommended by WHO).

Children with symptoms of zinc deficiency: rickets, malnutrition, growth retardation, frequently gastrointestinal disturbances, anorexia, sleeplessness, night-time crying, dry skin, dystrophia unguium (wrinkles, white spots, slow growth), weak resistance, frequently recurrent infections on skin and respiratory tract.

CONTRAINDICATIONS:

Hypersensitivity to any components of the drug.

PRECAUTIONS:

Use with caution in patients with renal impairment.

Prolonged use of zinc reduces the absorption of copper, resulting in anemia and thrombocytopenia.

PREGNANCY AND LACTATION:

Like as other drugs, it is advised to consult the physician before oral administration.

EFFECTS ON ABILITY TO DRIVE AND USE MACHINES:

The drug does not affect the ability to drive and use machines.

INTERACTIONS:

The zinc absorption is reduced by presence of tetracyclines, fluoroquinolones, iron- and copper-containing preparations. Concurrent administration of zinc gluconate and two above groups of antibiotic reduces the absorption of antibiotics.

ADVERSE EFFECTS:

Abdominal pain, indigestion, nausea, vomiting, diarrhea, gastric irritation and gastritis have been probably reported. These symptoms can be reduced by taking after meals.

Informs your physician about any adverse effects occur during the treatment.

OVERDOSAGE:

In acute poisoning, zinc salt is corrosive by forming chloride zinc under the action of stomach acid. Treatment is performed by giving milk or alkaline carbonate salts, or activated carbon. Emesis or gastric lavage should not be applied.

High-dose and long-term supplement of zinc or use of zinc contaminated hemodialysis solution causes copper deficiency, leading to sideroblastic anemia, neutropenia. Blood zinc level is reduced by using a chelating agent, sodium calcium edetate.

DOSAGE & ADMINISTRATION:

Unikids Zinc should be mixed with foods or dissolved in water before oral administration.

Supplement to the daily diet (taking after meals):

Children aged 6 months to 6 years: ½ sachet/ day.

Treatment of zinc deficiency in children (taking after meals):

Children weighed < 10 kg: 2 sachets once daily.

Children weighed 10 to 30 kg: 2 sachets x 1 - 3 times daily.

Adults and children (weighed > 30 kg): 4½ sachets x 1 - 3 times daily.

Supplement of zinc in children with acute and chronic diarrhea:

Children under 6 months of age: 1 sachet/ day, within 10 - 14 days.

Children over 6 months of age: 2 sachets/ day, within 10 - 14 days

Or as prescribed by the physician.

Read the directions carefully before use.

Consult the physician for more information.

Shelf-life: 36 months from the manufacturing date.

Storage conditions: Store in dry places, not exceeding 300C, protect from light.

Specifications: Manufacturer's.

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